STAT6 regulates natural helper cell proliferation during lung inflammation initiated by Alternaria.

@article{Doherty2012STAT6RN,
  title={STAT6 regulates natural helper cell proliferation during lung inflammation initiated by Alternaria.},
  author={Taylor A. Doherty and Naseem Khorram and Jinny E. Chang and H Kim and Peter Rosenthal and Michael Croft and David H. Broide},
  journal={American journal of physiology. Lung cellular and molecular physiology},
  year={2012},
  volume={303 7},
  pages={L577-88}
}
Asthma exacerbations can be caused by a number of factors, including the fungal allergen Alternaria, which is specifically associated with severe and near-fatal attacks. The mechanisms that trigger lung responses are unclear and might vary between allergens. A comparison between Alternaria, Aspergillus, Candida, and house dust mite, all allergens in humans, showed that only Alternaria promoted immediate innate airway eosinophilia within 12 h of inhalation in nonsensitized mice. Alternaria, but… CONTINUE READING
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