STAT3 regulation of glioblastoma pathogenesis.

  title={STAT3 regulation of glioblastoma pathogenesis.},
  author={N{\'u}ria de la Iglesia and Sidharth V. Puram and Azad Bonni},
  journal={Current molecular medicine},
  volume={9 5},
Malignant gliomas are the most common primary brain tumors. Despite efforts to find effective treatments, these tumors remain incurable. The failure of malignant gliomas to respond to conventional cancer therapies may reflect the unique biology of these tumors, underscoring the need for new approaches in their investigation. Recently, progress has been made in characterization of the molecular pathogenesis of glioblastoma using a developmental neurobiological perspective, by exploring the role… CONTINUE READING