STAT3 integrates cytokine and neurotrophin signals to promote sympathetic axon regeneration.


The transcription factor STAT3 has been implicated in axon regeneration. Here we investigate a role for STAT3 in sympathetic nerve sprouting after myocardial infarction (MI) - a common injury in humans. We show that NGF stimulates serine phosphorylation (S727) of STAT3 in sympathetic neurons via ERK1/2, in contrast to cytokine phosphorylation of Y705… (More)
DOI: 10.1016/j.mcn.2013.06.005


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