STAT3 inhibition, a novel approach to enhancing targeted therapy in human cancers (review).

@article{Wang2012STAT3IA,
  title={STAT3 inhibition, a novel approach to enhancing targeted therapy in human cancers (review).},
  author={Xiaochun Wang and Philip John Crowe and David Goldstein and Jia-lin Yang},
  journal={International journal of oncology},
  year={2012},
  volume={41 4},
  pages={1181-91}
}
Signal transducer and activator of transcription 3 (STAT3) regulates many critical functions in human normal and malignant tissues, such as differentiation, proliferation, survival, angiogenesis and immune function. Constitutive activation of STAT3 is implicated in a wide range of human cancers. As such, STAT3 has been studied as a tumour therapeutic target. This review aimed principally to summarise the updated research on STAT3 inhibition studies and their therapeutic potential in solid… CONTINUE READING
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Prognostic significance of STAT 3 and phosphorylated STAT 3 in human soft tissue tumorsa clinicopathological analysis

  • G Niu, KL Wright, M Huang
  • J Exp Clin Cancer Res
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