STAT3 and NF-κB are Simultaneously Suppressed in Dendritic Cells in Lung Cancer

Abstract

Tumour-induced dendritic cell (DC) dysfunction plays an important role in cancer immune escape. However, the underlying mechanisms are not yet fully understood, reflecting the lack of appropriate experimental models both in vivo and in vitro. In the present study, an in vitro study model for tumour-induced DC dysfunction was established by culturing DCs… (More)
DOI: 10.1038/srep45395

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