STAT3 Decoy Oligodeoxynucleotides-Loaded Solid Lipid Nanoparticles Induce Cell Death and Inhibit Invasion in Ovarian Cancer Cells

@inproceedings{Ma2015STAT3DO,
  title={STAT3 Decoy Oligodeoxynucleotides-Loaded Solid Lipid Nanoparticles Induce Cell Death and Inhibit Invasion in Ovarian Cancer Cells},
  author={Yanhui Ma and Xiaolei Zhang and Xiaoxuan Xu and Liang Shen and Yao Yao and Ziyan Yang and Peishu Liu},
  booktitle={PloS one},
  year={2015}
}
Recent advances in the synthesis of multi-functional nanoparticles have opened up tremendous opportunities for the targeted delivery of genes of interest. Cationic solid lipid nanoparticles (SLN) can efficiently bind nucleic acid molecules and transfect genes in vitro. Few reports have combined SLN with therapy using decoy oligodeoxynucleotides (ODN). In the present study, we prepared SLN to encapsulate STAT3 decoy ODN; then, the properties and in vitro behavior of SLN-STAT3 decoy ODN complexes… CONTINUE READING
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SHOWING 1-8 OF 8 CITATIONS

Applications of lipid nanoparticles in gene therapy.

  • European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V
  • 2016
VIEW 1 EXCERPT
CITES BACKGROUND

Nanoparticle-mediated inhibition of survivin to overcome drug resistance in cancer therapy.

  • Journal of controlled release : official journal of the Controlled Release Society
  • 2016
VIEW 1 EXCERPT
CITES METHODS

References

Publications referenced by this paper.
SHOWING 1-10 OF 49 REFERENCES

LC3 conjugation system in mammalian autophagy.

  • The international journal of biochemistry & cell biology
  • 2004
VIEW 6 EXCERPTS
HIGHLY INFLUENTIAL

Epithelial-mesenchymal transition in cervical carcinoma.

  • American journal of translational research
  • 2012
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Epithelial-mesenchymal transition—activating transcription factors—multifunctional regulators in cancer

M. Garg
  • World J Stem Cells
  • 2013
VIEW 1 EXCERPT

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