STAT1 is required for IFN-gamma-mediated gut-enriched Krüppel-like factor expression.

@article{Chen2002STAT1IR,
  title={STAT1 is required for IFN-gamma-mediated gut-enriched Kr{\"u}ppel-like factor expression.},
  author={Zhi Yi Chen and Jue Lon Shie and Chi Chuan Tseng},
  journal={Experimental cell research},
  year={2002},
  volume={281 1},
  pages={
          19-27
        }
}
Gut-enriched Krüppel-like factor (GKLF/KLF4), a member of the Krüppel-like factor family of transcription factors, has recently been shown to be associated with growth arrest in the colonic mucosa. Our laboratory has previously demonstrated that GKLF is one of the down-stream targets of interferon-gamma (IFN-gamma) in colon cancer cells, but the signaling pathway regulating GKLF expression is not known. In this report, we showed that IFN-gamma increased GKLF and interferon regulatory factor-1… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 12 CITATIONS

Similar Papers

Loading similar papers…