STAT1 as a key modulator of cell death.

  title={STAT1 as a key modulator of cell death.},
  author={Hun Sik Kim and M V Lee},
  journal={Cellular signalling},
  volume={19 3},
Signal transducers and activators of transcription (STATs) are latent cytoplasmic transcription factors that mediate various biological responses, including cell proliferation, survival, apoptosis, and differentiation. Among the members of the STAT family, accumulating evidence now indicates an important role for STAT1 in various forms of cell death. Depending upon stimuli or cell types, STAT1 can modulate a broad spectrum of cell death, comprising both apoptotic and non-apoptotic pathways… CONTINUE READING
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