STAG2 is a clinically relevant tumor suppressor in pancreatic ductal adenocarcinoma

@inproceedings{Evers2013STAG2IA,
  title={STAG2 is a clinically relevant tumor suppressor in pancreatic ductal adenocarcinoma},
  author={Lisa Evers and Pedro Antonio P{\'e}rez-Mancera and Elizabeth Lenkiewicz and Nanyun Tang and Daniela E. Aust and Thomas Kn{\"o}sel and Petra R{\"u}mmele and Tara K. Holley and Michelle Kimberly Kassner and Meraj Aziz and Ramesh K. Ramanathan and Daniel D. Von Hoff and Holly H. Yin and Christian Pilarsky and Michael T. Barrett},
  booktitle={Genome Medicine},
  year={2013}
}
Pancreatic ductal adenocarcinoma (PDA) is a highly lethal cancer characterized by complex aberrant genomes. A fundamental goal of current studies is to identify those somatic events arising in the variable landscape of PDA genomes that can be exploited for improved clinical outcomes. We used DNA content flow sorting to identify and purify tumor nuclei of PDA samples from 50 patients. The genome of each sorted sample was profiled by oligonucleotide comparative genomic hybridization and targeted… CONTINUE READING
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