ST6Gal-I expression in ovarian cancer cells promotes an invasive phenotype by altering integrin glycosylation and function

Abstract

BACKGROUND Ovarian adenocarcinoma is not generally discovered in patients until there has been widespread intraperitoneal dissemination, which is why ovarian cancer is the deadliest gynecologic malignancy. Though incompletely understood, the mechanism of peritoneal metastasis relies on primary tumor cells being able to detach themselves from the tumor… (More)
DOI: 10.1186/1757-2215-1-3

Topics

Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.