SSB recruitment of Exonuclease I aborts template-switching in Escherichia coli.


Misalignment of a nascent strand and the use of an alternative template during DNA replication, a process termed "template-switching", can give rise to frequent mutations and genetic rearrangements. Mutational hotspots are frequently found associated with imperfect inverted repeats ("quasipalindromes" or "QPs") in many organisms, including bacteriophage… (More)
DOI: 10.1016/j.dnarep.2017.05.007


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