SSA-MOA: a novel CTC isolation platform using selective size amplification (SSA) and a multi-obstacle architecture (MOA) filter.

@article{Kim2012SSAMOAAN,
  title={SSA-MOA: a novel CTC isolation platform using selective size amplification (SSA) and a multi-obstacle architecture (MOA) filter.},
  author={Minseok S Kim and Tae Seok Sim and Yeon Jeong Kim and Sun Soo Kim and Hyoyoung Jeong and Jong-Myeon Park and Hui-Sung Moon and Seung Il Kim and Ogan Gurel and Soo Suk Lee and Jeong-Gun Lee and Jae Chan Park},
  journal={Lab on a chip},
  year={2012},
  volume={12 16},
  pages={2874-80}
}
Circulating tumor cells (CTCs) have gained increasing attention as physicians and scientists learn more about the role these extraordinarily rare cells play in metastatic cancer. In developing CTC technology, the critical criteria are high recovery rates and high purity. Current isolation methods suffer from an inherent trade-off between these two goals. Moreover, ensuring minimal cell stress and robust reproducibility is also important for the clinical application of CTCs. In this paper, we… CONTINUE READING
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