SRPK1 is a poor prognostic indicator and a novel potential therapeutic target for human colorectal cancer

@inproceedings{Yi2018SRPK1IA,
  title={SRPK1 is a poor prognostic indicator and a novel potential therapeutic target for human colorectal cancer},
  author={Nan Yi and Mingbing Xiao and Feng Jiang and Zhaoxiu Liu and Wenkai Ni and Cuihua Lu and Runzhou Ni and Weichang Chen},
  booktitle={OncoTargets and therapy},
  year={2018}
}
  • Nan Yi, Mingbing Xiao, +5 authors Weichang Chen
  • Published in OncoTargets and therapy 2018
  • Medicine
  • Background Serine/arginine protein kinase 1 (SRPK1) is a protein kinase that belongs to the serine/arginine-rich domain family of splicing factors which are essential for splice-site selection, especially the modulation for RNA metabolism, localization, and translation. High expression of SRPK1 has been found in numerous human cancers, but its mechanism in colorectal cancer (CRC) is still rarely reported. Purpose To investigate the expression of SRPK1 in CRC tissues and cells and determine… CONTINUE READING

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