SR-BI does not require raft/caveola localisation for cholesteryl ester selective uptake in the human adrenal cell line NCI-H295R.

@article{Briand2003SRBIDN,
  title={SR-BI does not require raft/caveola localisation for cholesteryl ester selective uptake in the human adrenal cell line NCI-H295R.},
  author={Olivier Briand and Sophie Lestavel and Antoine Pilon and G{\'e}rard Torpier and J. -C. Fruchart and V{\'e}ronique Clavey},
  journal={Biochimica et biophysica acta},
  year={2003},
  volume={1631 1},
  pages={42-50}
}
Class B type I scavenger receptor (SR-BI) mediates the selective uptake of high-density lipoprotein (HDL)-derived cholesteryl esters (HDL-CE) in steroidogenic cells and hepatocytes. SR-BI is enriched in the caveolae of some cell types, genetically modified or not, and these domains have already been shown to constitute primary acceptors for HDL-CE. Nevertheless, the fate of caveola-free cell types has not yet been discussed.NCI-H295R, a human adrenal cell line, highly active in HDL-CE uptake… CONTINUE READING
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