SQID: an intensity-incorporated protein identification algorithm for tandem mass spectrometry.

@article{Li2011SQIDAI,
  title={SQID: an intensity-incorporated protein identification algorithm for tandem mass spectrometry.},
  author={Wenzhou Li and Li Ji and Jonathan Goya and Guanhong Tan and Vicki H. Wysocki},
  journal={Journal of proteome research},
  year={2011},
  volume={10 4},
  pages={1593-602}
}
To interpret LC-MS/MS data in proteomics, most popular protein identification algorithms primarily use predicted fragment m/z values to assign peptide sequences to fragmentation spectra. The intensity information is often undervalued, because it is not as easy to predict and incorporate into algorithms. Nevertheless, the use of intensity to assist peptide identification is an attractive prospect and can potentially improve the confidence of matches and generate more identifications. On the… CONTINUE READING
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