SPR surface enhanced fluorescence with a gold-coated corrugated sensor chip

@inproceedings{Reilly2006SPRSE,
  title={SPR surface enhanced fluorescence with a gold-coated corrugated sensor chip},
  author={Michael T. Reilly and Peter A. Nessing and Ernest F. Guignon and Michael A. Lynes and Salvador M. Fernandez},
  booktitle={SPIE BiOS},
  year={2006}
}
Our ultimate objective is to develop a low-cost, surface-enhanced fluorescence microarray detection system for highly multiplexed bioassays based on surface plasmon resonance (SPR) coupled fluorescence. For convenience we refer to this approach as SPREFE (SPR-coupled Enhanced Fluorescence Emission). Our implementation employs grating coupler sensor chips that consist of gold-coated plastic substrates with a periodic surface profile that enables resonant coupling of incident optical radiation… CONTINUE READING

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