SPON2, a newly identified target gene of MACC1, drives colorectal cancer metastasis in mice and is prognostic for colorectal cancer patient survival

@article{Schmid2016SPON2AN,
  title={SPON2, a newly identified target gene of MACC1, drives colorectal cancer metastasis in mice and is prognostic for colorectal cancer patient survival},
  author={Felicitas Schmid and Qinhao Wang and Matthew R. Huska and Miguel A. Andrade-Navarro and Margit Lemm and Iduna Fichtner and Mathias Dahlmann and Dennis Kobelt and W. Walther and J. Joshua Smith and Peter M. Schlag and Ulrike Stein},
  journal={Oncogene},
  year={2016},
  volume={35},
  pages={5942-5952}
}
MACC1 (metastasis associated in colon cancer 1) is a prognostic biomarker for tumor progression, metastasis and survival of a variety of solid cancers including colorectal cancer (CRC). Here we aimed to identify the MACC1-induced transcriptome and key players mediating the MACC1-induced effects in CRC. We performed microarray analyses using CRC cells ectopically overexpressing MACC1. We identified more than 1300 genes at least twofold differentially expressed, including the gene SPON2 (Spondin… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 4 times over the past 90 days. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-9 of 9 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 43 references

Similar Papers

Loading similar papers…