SPINE In VivoMonitoring of Rat Spinal CordMetabolism Using Hyperpolarized Carbon-13 MR Spectroscopic Imaging

SUMMARY: This study demonstrated the feasibility of using hyperpolarized C-MR spectroscopic imaging with [1-C]-pyruvate to evaluate in vivo spinal cord metabolism. High pyruvate and relatively small lactate signal were observed in the cervical spinal cords of naive rats. Lactate and pyruvate measures were similar for spinal cord and supratentorial brain… CONTINUE READING