SPINAL: scalable protein interaction network alignment

  title={SPINAL: scalable protein interaction network alignment},
  author={Ahmet Emre Aladağ and Cesim Erten},
  volume={29 7},
MOTIVATION Given protein-protein interaction (PPI) networks of a pair of species, a pairwise global alignment corresponds to a one-to-one mapping between their proteins. Based on the presupposition that such a mapping provides pairs of functionally orthologous proteins accurately, the results of the alignment may then be used in comparative systems biology problems such as function prediction/verification or construction of evolutionary relationships. RESULTS We show that the problem is NP… CONTINUE READING
Highly Influential
This paper has highly influenced 25 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS
Highly Cited
This paper has 120 citations. REVIEW CITATIONS
Recent Discussions
This paper has been referenced on Twitter 5 times over the past 90 days. VIEW TWEETS
59 Citations
43 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 59 extracted citations

121 Citations

Citations per Year
Semantic Scholar estimates that this publication has 121 citations based on the available data.

See our FAQ for additional information.


Publications referenced by this paper.
Showing 1-10 of 43 references

Similar Papers

Loading similar papers…