SPIDer: Saccharomyces protein-protein interaction database

  title={SPIDer: Saccharomyces protein-protein interaction database},
  author={Xiaomei Wu and Lei Zhu and Jie Guo and Cong Fu and Hongjun Zhou and Dong Dong and Zhenbo Li and Da-Yong Zhang and Kui Lin},
  journal={BMC Bioinformatics},
  pages={S16 - S16}
Since proteins perform their functions by interacting with one another and with other biomolecules, reconstructing a map of the protein-protein interactions of a cell, experimentally or computationally, is an important first step toward understanding cellular function and machinery of a proteome. Solely derived from the Gene Ontology (GO), we have defined an effective method of reconstructing a yeast protein interaction network by measuring relative specificity similarity (RSS) between two GO… CONTINUE READING


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