SPECT imaging with the serotonin transporter radiotracer [123I]p ZIENT in nonhuman primate brain.

Abstract

INTRODUCTION Serotonin dysfunction has been linked to a variety of psychiatric diseases; however, an adequate SPECT radioligand to probe the serotonin transporter system has not been successfully developed. The purpose of this study was to characterize and determine the in vivo selectivity of iodine-123-labeled 2beta-carbomethoxy-3beta-(4'-((Z)-2… (More)
DOI: 10.1016/j.nucmedbio.2010.03.007

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