SPECT and PET of the dopamine transporter in attention-deficit/hyperactivity disorder

@article{Krause2008SPECTAP,
  title={SPECT and PET of the dopamine transporter in attention-deficit/hyperactivity disorder},
  author={J. Krause},
  journal={Expert Review of Neurotherapeutics},
  year={2008},
  volume={8},
  pages={611 - 625}
}
  • J. Krause
  • Published 1 April 2008
  • Medicine
  • Expert Review of Neurotherapeutics
Abnormalities of frontostriatal circuits, which are modulated by dopamine, have been found by brain imaging studies in patients with attention-deficit/hyperactivity disorder (ADHD). With special radiolabeled ligands selective imaging of the dopamine transporter (DAT), which has a key function in dopamine metabolism, can be performed by SPECT and PET. Most of the studies showed a higher DAT availability in untreated patients with ADHD compared with controls. The relationship between DAT… Expand
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