SPECT and PET of the dopamine transporter in attention-deficit/hyperactivity disorder
@article{Krause2008SPECTAP, title={SPECT and PET of the dopamine transporter in attention-deficit/hyperactivity disorder}, author={J. Krause}, journal={Expert Review of Neurotherapeutics}, year={2008}, volume={8}, pages={611 - 625} }
Abnormalities of frontostriatal circuits, which are modulated by dopamine, have been found by brain imaging studies in patients with attention-deficit/hyperactivity disorder (ADHD). With special radiolabeled ligands selective imaging of the dopamine transporter (DAT), which has a key function in dopamine metabolism, can be performed by SPECT and PET. Most of the studies showed a higher DAT availability in untreated patients with ADHD compared with controls. The relationship between DAT… CONTINUE READING
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