SPC72: a spindle pole component required for spindle orientation in the yeast Saccharomyces cerevisiae.

@article{Sous1998SPC72AS,
  title={SPC72: a spindle pole component required for spindle orientation in the yeast Saccharomyces cerevisiae.},
  author={Sylvie Sou{\`e}s and Ian R. Adams},
  journal={Journal of cell science},
  year={1998},
  volume={111 ( Pt 18)},
  pages={2809-18}
}
The monoclonal antibody 78H6 recognises an 85 kDa component of the yeast spindle pole body. Here we identify and characterise this component as Spc72p, the product of YAL047C. The sequence of SPC72 contains potential coiled-coil domains; its overexpression induced formation of large polymers that were strictly localised at the outer plaque and at the bridge of the spindle pole body. Immunoelectron microscopy confirmed that Spc72p was a component of these polymers. SPC72 was found to be non… CONTINUE READING

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