SPARCL1 a novel player in cancer biology.

  title={SPARCL1 a novel player in cancer biology.},
  author={Filippo Gagliardi and Ashwin Narayanan and Pietro Mortini},
  journal={Critical reviews in oncology/hematology},
Matricellular proteins are secreted, nonstructural proteins, involved in the mediation of molecular interactions between cells and extracellular microenvironment. They include several, structurally unrelated, members and their homologs. Among these a particularly interesting one is SPARCL1 due to its potential interactions in tumor biology. SPARCL1 is a secreted glycoprotein, belonging to SPARC family of matricellular proteins. It is implicated in the regulation of cell adhesion, migration, and… CONTINUE READING