SPAK and OSR1 Sensitivity of Excitatory Amino Acid Transporter EAAT3.

Abstract

BACKGROUND/AIMS Kinases involved in the regulation of epithelial transport include SPAK (SPS1-related proline/alanine-rich kinase) and OSR1 (oxidative stress-responsive kinase 1). SPAK and OSR1 are both regulated by WNK (with-no-K(Lys)) kinases. The present study explored whether SPAK and/or OSR1 influence the excitatory amino acid transporter EAAT3, which… (More)
DOI: 10.1159/000433567

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