SOXE neofunctionalization and elaboration of the neural crest during chordate evolution

@inproceedings{Tai2016SOXENA,
  title={SOXE neofunctionalization and elaboration of the neural crest during chordate evolution},
  author={Andrew Tai and Martin Cheung and Yong-heng Huang and Ralf Jauch and Marianne E Bronner and Kathryn Song Eng Cheah},
  booktitle={Scientific reports},
  year={2016}
}
During chordate evolution, two genome-wide duplications facilitated acquisition of vertebrate traits, including emergence of neural crest cells (NCCs), in which neofunctionalization of the duplicated genes are thought to have facilitated development of craniofacial structures and the peripheral nervous system. How these duplicated genes evolve and acquire the ability to specify NC and their derivatives are largely unknown. Vertebrate SoxE paralogues, most notably Sox9/10, are essential for NC… CONTINUE READING
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