SOX2-specific adaptive immunity and response to immunotherapy in non-small cell lung cancer

@inproceedings{Dhodapkar2013SOX2specificAI,
  title={SOX2-specific adaptive immunity and response to immunotherapy in non-small cell lung cancer},
  author={Kavita M. Dhodapkar and Scott N. Gettinger and Rituparna Das and Henry A. Zebroski and Madhav V Dhodapkar},
  booktitle={Oncoimmunology},
  year={2013}
}
Immunotherapeutic strategies including the blockade of programmed death 1 (PD-1) receptors hold promise for the treatment of various cancers including non-small cell lung carcinoma (NSCLC). Preclinical data suggest that pre-existing tumor immunity is important for disease regression upon checkpoint blockade-based therapies. However, the nature of antigen-specific T-cell responses that correlate with the clinical response to immunotherapy in NSCLC patients is not known. The embryonic stem cell… CONTINUE READING
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