SNaPshot minisequencing to resolve mitochondrial macro‐haplogroups found in Africa

  title={SNaPshot minisequencing to resolve mitochondrial macro‐haplogroups found in Africa},
  author={C. Schlebusch and T. Naidoo and H. Soodyall},
  • C. Schlebusch, T. Naidoo, H. Soodyall
  • Published 2009
  • Biology, Medicine
  • African mitochondrial DNA (mtDNA) haplogroups are divided into seven macro‐haplogroups (L0′1′2′3′4′5′6), while the rest of the world's lineages are classified as subgroups of macro‐haplogroups M, N and R. The most common approach to characterizing mtDNA variation is the sequencing of hypervariable segments I and II of the non‐coding control region of the molecule. Given the higher mutation rate within the control region compared with the coding regions of the molecule, recurrent mutations in… CONTINUE READING
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