SNaPshot minisequencing to resolve mitochondrial macro‐haplogroups found in Africa

@article{Schlebusch2009SNaPshotMT,
  title={SNaPshot minisequencing to resolve mitochondrial macro‐haplogroups found in Africa},
  author={Carina M. Schlebusch and Thijessen Naidoo and Himla Soodyall},
  journal={ELECTROPHORESIS},
  year={2009},
  volume={30}
}
African mitochondrial DNA (mtDNA) haplogroups are divided into seven macro‐haplogroups (L0′1′2′3′4′5′6), while the rest of the world's lineages are classified as subgroups of macro‐haplogroups M, N and R. The most common approach to characterizing mtDNA variation is the sequencing of hypervariable segments I and II of the non‐coding control region of the molecule. Given the higher mutation rate within the control region compared with the coding regions of the molecule, recurrent mutations in… 
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