SNX5, a new member of the sorting nexin family, binds to the Fanconi anemia complementation group A protein.

@article{Otsuki1999SNX5AN,
  title={SNX5, a new member of the sorting nexin family, binds to the Fanconi anemia complementation group A protein.},
  author={Tetsuya Otsuki and Sachiko Kajigaya and Keiya Ozawa and Johnson M. Liu},
  journal={Biochemical and biophysical research communications},
  year={1999},
  volume={265 3},
  pages={630-5}
}
The function of the Fanconi anemia complementation group A (FANCA) protein remains unclear. To investigate possible protein-protein interactions, we performed yeast two-hybrid screening using a FANCA fragment as bait. Sorting nexin 5 (SNX5), a new member of the human SNX family, was identified as a putative FANCA-binding protein. The interaction between FANCA and SNX5 was confirmed by immunoprecipitation studies. All members of the SNX family have a characteristic amino acid region termed the… CONTINUE READING

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