SNR1 is an essential subunit in a subset of Drosophila brm complexes, targeting specific functions during development.

@article{Zraly2003SNR1IA,
  title={SNR1 is an essential subunit in a subset of Drosophila brm complexes, targeting specific functions during development.},
  author={Claudia B. Zraly and Daniel Marenda and Runjhun Nanchal and Giacomo Cavalli and Christian Muchardt and Andrew K. Dingwall},
  journal={Developmental biology},
  year={2003},
  volume={253 2},
  pages={291-308}
}
The snr1 gene of Drosophila melanogaster encodes a conserved component of the multiprotein Brahma (Brm) complex, a counterpart to the SWI/SNF complexes that participate in ATP-dependent chromatin remodeling. Loss-of-function and null mutations in the snr1 gene reveal its essential role in Drosophila development. We identified new mutant alleles and ectopically expressed deleted forms to dissect the specific functions of SNR1. Somatic and germ cell clone analyses confirmed its requirement in a… CONTINUE READING
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