SNR Dependence of Optimal Parameters for Apparent Diffusion Coefficient Measurements

@article{Saritas2011SNRDO,
  title={SNR Dependence of Optimal Parameters for Apparent Diffusion Coefficient Measurements},
  author={Emine Ulku Saritas and Jin Hyung Lee and Dwight G. Nishimura},
  journal={IEEE Transactions on Medical Imaging},
  year={2011},
  volume={30},
  pages={424-437}
}
Optimizing the diffusion-weighted imaging (DWI) parameters (i.e., the b-value and the number of image averages) to the tissue of interest is essential for producing high-quality apparent diffusion coefficient (ADC) maps. Previous investigation of this optimization was performed assuming Gaussian noise statistics for the ADC map, which is only valid for high signal-to-noise ratio (SNR) imaging. In this work, the true statistics of the noise in ADC maps are derived, followed by an optimization of… CONTINUE READING