SNPs in the FCER1A Gene Region Show No Association with Allergic Rhinitis in a Han Chinese Population

@inproceedings{Zhang2010SNPsIT,
  title={SNPs in the FCER1A Gene Region Show No Association with Allergic Rhinitis in a Han Chinese Population},
  author={Yuan Zhang and Su Xia Duan and Xiaoping Lin and Wei Zhang and Na Meng and Liping Zhao and Yan Zhao and Demin Han and Luo Zhang},
  booktitle={PloS one},
  year={2010}
}
BACKGROUND Immunoglobulin E (IgE) is a central player in the allergic response, and raised total IgE levels are considered as an indicator of atopy or potential development of atopy. A recent genome-wide scan in a German population-based cohort of adults identified the gene encoding the alpha chain of the high affinity receptor for IgE (FCER1A) as a susceptibility locus influencing total serum IgE levels. The aim of this study was to investigate whether the polymorphisms in the FCER1A gene are… CONTINUE READING

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