SNPs in dopamine D2 receptor gene (DRD2) and norepinephrine transporter gene (NET) are associated with continuous performance task (CPT) phenotypes in ADHD children and their families.

@article{Kollins2008SNPsID,
  title={SNPs in dopamine D2 receptor gene (DRD2) and norepinephrine transporter gene (NET) are associated with continuous performance task (CPT) phenotypes in ADHD children and their families.},
  author={Scott Haden Kollins and Arthur D. Anastopoulos and Ave M Lachiewicz and Daniel Fitzgerald and Erin Morrissey-Kane and Melanie E Garrett and Shelley Keatts and Allison E. Ashley-Koch},
  journal={American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics},
  year={2008},
  volume={147B 8},
  pages={1580-8}
}
Haplotype-tagging SNP analyses were conducted to identify molecular genetic substrates of quantitative phenotypes derived from performance on a Continuous Performance Task (CPT). Three hundred sixty-four individuals were sampled from 152 families ascertained on the basis of at least one child having ADHD. Probands, their affected and unaffected siblings, and parents were administered a CPT. Four different components of performance were analyzed and tested for association with SNPs from 10… CONTINUE READING
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