SNP panel identification assay (SPIA): a genetic-based assay for the identification of cell lines

  title={SNP panel identification assay (SPIA): a genetic-based assay for the identification of cell lines},
  author={Francesca Demichelis and Heidi Greulich and Jill Macoska and Rameen Beroukhim and William R. Sellers and Levi A. Garraway and Mark A. Rubin},
  booktitle={Nucleic acids research},
Translational research hinges on the ability to make observations in model systems and to implement those findings into clinical applications, such as the development of diagnostic tools or targeted therapeutics. Tumor cell lines are commonly used to model carcinogenesis. The same tumor cell line can be simultaneously studied in multiple research laboratories throughout the world, theoretically generating results that are directly comparable. One important assumption in this paradigm is that… CONTINUE READING


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