SNP characteristics predict replication success in association studies


Successful independent replication is the most direct approach for distinguishing real genotype–disease associations from false discoveries in genome-wide association studies (GWAS). Selecting SNPs for replication has been primarily based on P values from the discovery stage, although additional characteristics of SNPs may be used to improve replication… (More)
DOI: 10.1007/s00439-014-1493-6


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