SNP characteristics predict replication success in association studies

Abstract

Successful independent replication is the most direct approach for distinguishing real genotype–disease associations from false discoveries in genome-wide association studies (GWAS). Selecting SNPs for replication has been primarily based on P values from the discovery stage, although additional characteristics of SNPs may be used to improve replication… (More)
DOI: 10.1007/s00439-014-1493-6

Topics

10 Figures and Tables

Slides referencing similar topics