SNP-SNP interactions in breast cancer susceptibility

@article{Onay2005SNPSNPII,
  title={SNP-SNP interactions in breast cancer susceptibility},
  author={Ven{\"u}s {\"U}mmiye Onay and Laurent Briollais and J. A. G. Knight and Ellen Shi and Yuanyuan Wang and Sean Wells and Hong Li and Isaac Rajendram and Irene L Andrulis and Hilmi Ozçelik},
  journal={BMC Cancer},
  year={2005},
  volume={6},
  pages={114 - 114}
}
Breast cancer predisposition genes identified to date (e.g., BRCA1 and BRCA2) are responsible for less than 5% of all breast cancer cases. Many studies have shown that the cancer risks associated with individual commonly occurring single nucleotide polymorphisms (SNPs) are incremental. However, polygenic models suggest that multiple commonly occurring low to modestly penetrant SNPs of cancer related genes might have a greater effect on a disease when considered in combination. In an attempt to… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 82 extracted citations

Odds Ratio-Based Genetic Algorithm for Prediction of SNP-SNP Interactions in Breast Cancer Association Study

2012 26th International Conference on Advanced Information Networking and Applications Workshops • 2012
View 4 Excerpts
Highly Influenced

Association of three common BARD1 variants with cancer susceptibility: a system review and meta-analysis.

International journal of clinical and experimental medicine • 2015
View 4 Excerpts
Highly Influenced

References

Publications referenced by this paper.
Showing 1-10 of 82 references

The effect of cyclin D1 (CCND1) G870A-polymorphism on breast cancer risk is modified by oxidative stress among Chinese women

M Ceschi, CL Sun, +3 authors N Probst-Hensch
Carcinogenesis • 2005
View 4 Excerpts
Highly Influenced

An introduction to the bootstrap

B Efron, RJ Tibshirani
1993
View 4 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…