SNAREs in opposing bilayers interact in a circular array to form conducting pores.

@article{Cho2002SNAREsIO,
  title={SNAREs in opposing bilayers interact in a circular array to form conducting pores.},
  author={S. Cho and Marie Kelly and Katherine T Rognlien and Jin Ah Cho and J. K. Heinrich H{\"o}rber and Bhanu P Jena},
  journal={Biophysical journal},
  year={2002},
  volume={83 5},
  pages={2522-7}
}
The process of fusion at the nerve terminal is mediated via a specialized set of proteins in the synaptic vesicles and the presynaptic membrane. Three soluble N-ethylmaleimide-sensitive factor (NSF)-attachment protein receptors (SNAREs) have been implicated in membrane fusion. The structure and arrangement of these SNAREs associated with lipid bilayers were examined using atomic force microscopy. A bilayer electrophysiological setup allowed for measurements of membrane conductance and… CONTINUE READING
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