SNAP-25 in Major Psychiatric Disorders: A Review

@article{Najera2019SNAP25IM,
  title={SNAP-25 in Major Psychiatric Disorders: A Review},
  author={Katherine Najera and B. Matthew Fagan and Peter M. Thompson},
  journal={Neuroscience},
  year={2019},
  volume={420},
  pages={79-85}
}
Synaptosomal Associated Protein-25 kilodaltons (SNAP-25) is an integral member of the SNARE complex. This complex is essential for calcium-triggered synaptic vesicular fusion and release of neurotransmitters into the synaptic cleft. In addition to neurotransmission, SNAP-25 is associated with insulin release, the regulation of intracellular calcium, and neuroplasticity. Because of SNAP-25's varied and crucial biological roles, the consequences of changes in this protein can be seen in both the… Expand
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