SNAP-25, a SNARE protein, inhibits two types of K channels in esophageal smooth muscle.

@article{Ji2002SNAP25AS,
  title={SNAP-25, a SNARE protein, inhibits two types of K channels in esophageal smooth muscle.},
  author={Junzhi Ji and Anne Marie M Salapatek and Helena Lau and Guotang Wang and Herbert Y Gaisano and Nicholas E. Diamant},
  journal={Gastroenterology},
  year={2002},
  volume={122 4},
  pages={
          994-1006
        }
}
BACKGROUND & AIMS The plasma membrane-associated soluble N-ethylmaleimide-sensitive factors attachment protein receptors (SNAREs), synaptosome-associated protein of 25 kilodaltons (SNAP-25), and syntaxin 1A, have been found to physically interact with and functionally modify membrane-spanning ion channels. Studies were performed in cat esophageal body and lower esophageal sphincter (LES) smooth muscle to (1) show the presence of SNAP-25, and (2) determine whether SNAP-25 affects K+ channel… CONTINUE READING
Highly Cited
This paper has 23 citations. REVIEW CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 15 extracted citations

Distinct modulation of Kv1.2 channel gating by wild type, but not open form, of syntaxin-1A.

American journal of physiology. Gastrointestinal and liver physiology • 2007
View 3 Excerpts
Highly Influenced