Corpus ID: 39718715


  author={Astrid M Bakker-Zierikzee and Marcel G. Smits},
Nutrition influences sleep. Drinking a glass of warm milk in the evening has been a long term tradition in several cultures. Although most of these reports are anecdotal, several milk components have been associated with sleep, such as tryptophan, bioactive peptides and magnesium. The widest researched dairy component in relation to sleep is tryptophan. Tryptophan is the precursor of serotonin. A good source of tryptophan is alpha-lactalbumin, a major protein found in whey. Evening alpha… Expand
Efficacy of low‐fat milk and yogurt fortified with encapsulated vitamin D3 on improvement in symptoms of insomnia and quality of life: Evidence from the SUVINA trial
Fortified low‐fat milk containing 1,500 IU vitamin D3 can improve insomnia symptoms and subsequently quality of life. Expand
Evaluating the associations of consumption of non-red meat protein sources and flavor preferences on sleeping patterns among older adults in China
Chinese public health practitioners and nutritionists should promote the best non-red meat protein options for improving better sleep among the older adults and the oldest-old in China. Expand


Evening intake of alpha-lactalbumin increases plasma tryptophan availability and improves morning alertness and brain measures of attention.
BACKGROUND Brain serotonin function is thought to promote sleep regulation and cognitive processes, whereas sleep abnormalities and subsequent behavioral decline are often attributed to deficientExpand
A tryptic hydrolysate from bovine milk αS1-casein improves sleep in rats subjected to chronic mild stress
The protective effect of the alphaS1-casein hydrolysate on sleep during exposure to chronic mild stress conditions may be mediated by modulation of the central adrenergic response. Expand
BRIEF COMMUNICATION: Sleep Induced by L-Tryptophan: Effect of Dosages within the Normal Dietary Intake
The present laboratory study extends the dose-response curve downward, comparing doses of ¼ g, ½ g, and 1 g of L-tryptophan with placebo, in 15 mild insomniacs (subjects who reported sleep latencies of over 30 minutes). Expand
Whey protein rich in alpha-lactalbumin increases the ratio of plasma tryptophan to the sum of the other large neutral amino acids and improves cognitive performance in stress-vulnerable subjects.
The results suggest that dietary protein rich in alpha-lactalbumin improves cognitive performance in stress-vulnerable subjects via increased brain tryptophan and serotonin activities. Expand
Protein source tryptophan versus pharmaceutical grade tryptophan as an efficacious treatment for chronic insomnia
Protein source tryptophan with carbohydrate alone proved effective in significantly reducing time awake during the night, and is comparable to pharmaceutical grade tryPTophan for the treatment of insomnia. Expand
Effects of a tryptic hydrolysate from bovine milk αS1–casein on hemodynamic responses in healthy human volunteers facing successive mental and physical stress situations
The results suggest an antistress profile of this αS1–casein hydrolysate in human subjects on the basis of blood pressure and cortisol changes. Expand
Magnesium therapy for periodic leg movements-related insomnia and restless legs syndrome: an open pilot study.
It is indicated that magnesium treatment may be a useful alternative therapy in patients with mild or moderate RLS-or PLMS-related insomnia and further investigations regarding the role of magnesium in the pathophysiology of RLS and placebo-controlled studies need to be performed. Expand
Are changes in beliefs and attitudes about sleep related to sleep improvements in the treatment of insomnia?
The results showed that CBT and COMB treatments produced greater improvements of beliefs and attitudes about sleep at posttreatment than PCT and PLA, and were associated with better maintenance of sleep improvements at follow-ups. Expand
Characterization of α‐casozepine, a tryptic peptide from bovine αs1‐casein with benzodiazepine‐like activity
Caseins are a known source of biologically active peptides. In this study, we have shown evidence of a novel anxiolytic activity in a tryptic hydrolysate of bovine αs1‐casein. Injection of 3 mg/kg ofExpand
Protein source tryptophan versus pharmaceutical
  • Am J Clin Nutr. 2005;81:1026-1033
  • 2005