SLC26 Cl-/HCO3- exchangers in the kidney: roles in health and disease.

@article{Soleimani2013SLC26CE,
  title={SLC26 Cl-/HCO3- exchangers in the kidney: roles in health and disease.},
  author={Manoocher Soleimani},
  journal={Kidney international},
  year={2013},
  volume={84 4},
  pages={657-66}
}
Solute-linked carrier 26 (SLC26) isoforms constitute a conserved family of anion transporters with 10 distinct members. Except for SLC26A5 (prestin), all can operate as multifunctional anion exchangers, with three members (SLC26A7, SLC26A9, and SLC26A11) also capable of functioning as chloride channels. Several SLC26 isoforms can specifically mediate Cl(-)/HCO(3)(-) exchange. These include SLC26A3, A4, A6, A7, A9, and A11, which are expressed in the kidney except for SLC26A3 (DRA), which is… CONTINUE READING
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