SLC23A1 polymorphism rs6596473 in the vitamin C transporter SVCT1 is associated with aggressive periodontitis.

@article{Jong2014SLC23A1PR,
  title={SLC23A1 polymorphism rs6596473 in the vitamin C transporter SVCT1 is associated with aggressive periodontitis.},
  author={T de Jong and Arne Jochens and Yvonne Jockel-Schneider and Inga Harks and H Dommisch and Christian Graetz and Friederike Flachsbart and Ingmar Staufenbiel and J{\"o}rg Eberhard and Mathias Folwaczny and Barbara Noack and Joerg Meyle and Peter Eickholz and Christian Gieger and Harald Grallert and Wolfgang Lieb and Andre Franke and Almut Nebel and Stefan Schreiber and Christof Doerfer and S\oeren Jepsen and Corinna Bruckmann and Ubele Van der Velden and Bruno G. Loos and Arne S. Schaefer},
  journal={Journal of clinical periodontology},
  year={2014},
  volume={41 6},
  pages={531-40}
}
AIM Identification of variants within genes SLC23A1 and SLC23A2 coding for vitamin C transporter proteins associated with aggressive (AgP) and chronic periodontitis (CP). MATERIAL AND METHODS Employment of three independent case-control samples of AgP (I. 283 cases, 979 controls; II. 417 cases, 1912 controls; III. 164 cases, 357 controls) and one sample of CP (1359 cases, 1296 controls). RESULTS Stage 1: Among the tested single-nucleotide polymorphisms (SNPs), the rare allele (RA) of… CONTINUE READING