SLC11A1 and VDR gene variants and susceptibility to tuberculosis and disease progression in East India.

@article{Singh2011SLC11A1AV,
  title={SLC11A1 and VDR gene variants and susceptibility to tuberculosis and disease progression in East India.},
  author={Anamika Singh and John P. Gaughan and Vijendra Kumar Kashyap},
  journal={The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease},
  year={2011},
  volume={15 11},
  pages={1468-74, i}
}
SETTING Despite efforts at disease control, the incidence of tuberculosis (TB) remains high in India. OBJECTIVE To assess the role of VDR and SLC11A1 gene polymorphisms in the development of pulmonary TB (PTB) in an ethnically matched population of India. DESIGN In this case-control study, five variants (INT4/ rs3731865, 823C/T/rs17221959, D543N/rs17235409, 577G/A/rs1059823 and TGTG deletion-3UTR/rs172 35416) of SLC11A1 and three (BsmI/rs1544410, FokI/ rs10735810 and TaqI/rs731236) of the… CONTINUE READING
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