SKY and FISH analysis of radiation-induced chromosome aberrations: a comparison of whole and partial genome analysis.

Abstract

For a retrospective dose estimation of human exposure to ionising radiation, a partial genome analysis is routinely used to quantify radiation-induced chromosome aberrations. For this purpose, fluorescence in situ hybridisation (FISH) with whole chromosome painting probes for selected chromosomes is usually applied covering about 20% of the whole genome… (More)

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