SKA3 Promotes tumor growth by regulating CDK2/P53 phosphorylation in hepatocellular carcinoma

@article{Hou2019SKA3PT,
  title={SKA3 Promotes tumor growth by regulating CDK2/P53 phosphorylation in hepatocellular carcinoma},
  author={Yuchen Hou and Ziming Wang and Shanzhou Huang and Chengjun Sun and Jingya Zhao and Jiayu Shi and Zhongqiu Li and Zekang Wang and Xiaoshun He and Nga Lei Tam and Linwei Wu},
  journal={Cell Death \& Disease},
  year={2019},
  volume={10}
}
  • Yuchen Hou, Ziming Wang, +8 authors Linwei Wu
  • Published 2019
  • Biology, Medicine
  • Cell Death & Disease
Spindle and kinetochore-related complex subunit 3 (SKA3) is a component of the spindle and kinetochore-related complexes and is essential for accurate timing of late mitosis. However, the relationship between SKA3 and hepatocellular carcinoma (HCC) has not yet been fully elucidated. Gene expression omnibus (GEO) (GSE62232, GSE45436, GSE6764, and GSE36376) and The Cancer Atlas (TCGA) datasets were analyzed to identify differential expression genes. Cell proliferation ability was analyzed using… Expand
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Transcript levels of spindle and kinetochore-associated complex 1/3 as prognostic biomarkers correlated with immune infiltrates in hepatocellular carcinoma
TLDR
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