SK HEP-1: A human cell line of endothelial origin

  title={SK HEP-1: A human cell line of endothelial origin},
  author={Sue C. Heffelfinger and Hal H. Hawkins and Jim Barrish and Linda M. Taylor and Gretchen J. Darlington},
  journal={In Vitro Cellular & Developmental Biology - Animal},
SK-HEP-1 is an immortal, human cell line derived from the ascitic fluid of a patient with adenocarcinoma of the liver. We have determined that these cells are of endothelial origin. Despite the location of the tumor from which SK HEP-1 was derived, the cell line does not have properties of hepatocytes. Northern blot analysis of total cellular RNA shows no messenger RNA for the hepatic-specific proteins albumin, alpha-fibrinogen, or gamma-fibrinogen. Endothelial characteristics are seen by… CONTINUE READING
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