SIV replication in the infected rhesus macaque is limited by the size of the preexisting TH17 cell compartment.

@article{HartiganOConnor2012SIVRI,
  title={SIV replication in the infected rhesus macaque is limited by the size of the preexisting TH17 cell compartment.},
  author={Dennis J. Hartigan-O'Connor and Kristina Abel and Koen K A Van Rompay and Bittoo Kanwar and Joseph M McCune},
  journal={Science translational medicine},
  year={2012},
  volume={4 136},
  pages={136ra69}
}
The mechanisms by which some HIV-infected subjects resist disease progression, whereas others progress rapidly, are incompletely understood. Viral and host genetic factors, such as nef deletions and major histocompatibility complex alleles, explain a portion of the observed variability. However, it has been difficult to identify host immune functions that may be present before infection and that allow resistance to lentiviral disease progression. Here, we show that simian immunodeficiency virus… CONTINUE READING
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