SIV-induced instability of the chimpanzee gut microbiome.

@article{Moeller2013SIVinducedIO,
  title={SIV-induced instability of the chimpanzee gut microbiome.},
  author={Andrew H Moeller and Meghan Shilts and Yingying Li and Rebecca S. Rudicell and Elizabeth V Lonsdorf and Anne E Pusey and Michael L Wilson and Beatrice H Hahn and Howard Ochman},
  journal={Cell host & microbe},
  year={2013},
  volume={14 3},
  pages={
          340-5
        }
}
Simian immunodeficiency virus of chimpanzees (SIVcpz) is the ancestor of human immunodeficiency virus type 1 (HIV-1), the etiologic agent of acquired immunodeficiency syndrome (AIDS) in humans. Like HIV-1-infected humans, SIVcpz-infected chimpanzees can develop AIDS-like symptoms. Because SIVcpz/HIV-1 may disrupt regulation of the gut microbiome and because it has not been possible to sample individual humans pre- and postinfection, we investigated the influence of infection on gut communities… CONTINUE READING

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