SIRT3 Acts as a Neuroprotective Agent in Rotenone-Induced Parkinson Cell Model

Abstract

SIRT3 is a member of Sirtuins family, which belongs to NAD+ dependent class III histone deacetylases. Emerging evidence suggests that SIRT3 plays a pivotal role in regulating mitochondrial function. Mitochondrial dysfunction is a main pathogenesis of Parkinson’s disease (PD). Here, we have investigated the protective effect of SIRT3 for PD cell model. The… (More)
DOI: 10.1007/s11064-016-1892-2

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Cite this paper

@article{Zhang2016SIRT3AA, title={SIRT3 Acts as a Neuroprotective Agent in Rotenone-Induced Parkinson Cell Model}, author={Jing-yi Zhang and Yong-ning Deng and Meng Zhang and Hua Su and Qiu-min Qu}, journal={Neurochemical Research}, year={2016}, volume={41}, pages={1761-1773} }