SIRT1 and energy metabolism.

  title={SIRT1 and energy metabolism.},
  author={Xiaoling Li},
  journal={Acta biochimica et biophysica Sinica},
  volume={45 1},
Sirtuin 1 (SIRT1) is the most conserved mammalian NAD(+)-dependent protein deacetylase that has emerged as a key metabolic sensor in various metabolic tissues. In response to different environmental stimuli, SIRT1 directly links the cellular metabolic status to the chromatin structure and the regulation of gene expression, thereby modulating a variety of cellular processes such as energy metabolism and stress response. Recent studies have shown that SIRT1 controls both glucose and lipid… CONTINUE READING


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